Tag Archives: CYP2C9

What are the CYP2CP substrates that piperine might interfere with?

CYP2C9 Substrates

  • Alosetron (Lotronex)
  • Bosentan (Tracleer)
  • Candesartan (Atacand)
  • Celecoxib (Celebrex)
  • Chlorpropamide (eg, Diabinese)
  • Diclofenac (Voltaren)
  • Dronabinol (Marinol)
  • Flurbiprofen (Ansaid)
  • Fluvastatin (Lescol)
  • Glimepiride (Amaryl)
  • Glipizide (Glucotrol)
  • Glyuride (DiaBeta)
  • Ibuprofen (eg, Motrin, Advil)
  • Indomethacin (Indocin)
  • Irbesartan (Avapro)
  • Losartan (Cozaar)
  • Meloxicam (Mobic)
  • Montulukast (Singulair)
  • Naproxen (eg, Aleve)
  • Nateglinide (Starlix)
  • Phenobarbital
  • Phenytoin (eg, Dilantin)
  • Piroxicam (Feldene)
  • Rosiglitazone (Avandia)
  • Rosuvastatin (Crestor)
  • Sulfamethoxazole
  • Tolbutamide
  • Torsemide (Demadex)
  • Valsartan (Diovan)
  • Warfarin (Coumadin)

CYP2C9 Inducers

  • Aminoglutethimide
  • Barbiturates
  • Bosentan (Tracleer)
  • Carbamazepine (eg. Tegretol)
  • Griseofulvin
  • Phenytoin (eg. Dilantin)
  • Primidone
  • Rifabutin
  • Rifampin (eg, Rifadin)
  • Rifapentine
  • St. John’s Wort