CYP2C9 Substrates

• Alosetron (Lotronex)
• Bosentan (Tracleer)
• Candesartan (Atacand)
• Celecoxib (Celebrex)
• Chlorpropamide (eg, Diabinese)
• Diclofenac (Voltaren)
• Dronabinol (Marinol)
• Flurbiprofen (Ansaid)
• Fluvastatin (Lescol)
• Glimepiride (Amaryl)
• Glipizide (Glucotrol)
• Glyuride (DiaBeta)
• Ibuprofen (eg, Motrin, Advil)
• Indomethacin (Indocin)
• Irbesartan (Avapro)
• Losartan (Cozaar)
• Meloxicam (Mobic)
• Montulukast (Singulair)
• Naproxen (eg, Aleve)
• Nateglinide (Starlix)
• Phenobarbital
• Phenytoin (eg, Dilantin)
• Piroxicam (Feldene)
• Rosiglitazone (Avandia)
• Rosuvastatin (Crestor)
• Sulfamethoxazole
• Tolbutamide
• Torsemide (Demadex)
• Valsartan (Diovan)
• Warfarin (Coumadin)

CYP2C9 Inducers

• Aminoglutethimide
• Barbiturates
• Bosentan (Tracleer)
• Carbamazepine (eg. Tegretol)
• Griseofulvin
• Phenytoin (eg. Dilantin)
• Primidone
• Rifabutin
• Rifampin (eg, Rifadin)
• Rifapentine
• St. John’s Wort